Distortion

The artifact Distortion locks a randomly selected ability for one minute, and then locks another one. It can be found in the Damp Caverns: In one variant of the map, an artifact gate can be found in the upper-right. Along the right edge of the top-most platform there will be a short vine leading down to the gate. The artifact will not yet be present. Just off the right edge of the screen are some smaller ledges which are only reachable with a Photon Jetpack, 2 Hopoo Feathers, or 7(?) Rusty Jetpacks (and in each case, perhaps a couple Paul's Goat Hooves). The jump can also be made using the Spirit artifact at minimum HP and any ability that increases movespeed (tested Acrid and Commando) or with Loader's hook. The box-shaped object covered in fungus is a switch that cannot be directly damaged, but will activate with any area damage such as explosions. (Jumping with Headstompers will work, as will the Enforcer's  skill.) "Dying" by going off the top edge of the screen will respawn you above the artifact gate, which now holds the Distortion artifact.