Thallium

Tactics

 * Keep in mind that does not stack, so obtaining more than one is pointless.

Character Synergies

 * Characters with high attack speed, such as  tend to make better use of, as higher attack speeds will allow for more frequent activation of the item.

Item Synergies

 * Items that increase crit chance, such as and, will allow  to activate more often.
 * Items that increase attack speed, such as and, will also allow  to activate more often.
 * Because increases both attack speed and crit chance, it can be especially beneficial when used in conjunction with this item.

Trivia

 * The description may be a reference to Thallium poisoning, which is known to be slow-acting, painful, and easy to misdiagnose.