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Fire Emblem Warriors: Three Hopes - The Loop
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Helfire Tincture is a Lunar Equipment in Risk of Rain 2.
Like all Lunar items, the Tincture has a powerful effect and a drawback. Activating the item starts damaging the player at 5% max hp per seconds rate. All nearby allies take half of this damage, and all nearby enemies take 24 times the damage.
Completing the "Multikill!" Challenge unlocks this item.